Tranexamic Acid Cosmetic Use

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Last update: 2018-07-27 09:15
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Technical Data sheet

Tranexamic Acid CAS No.: 1197-18-8

Specification

Item

Specifications

Description

White crystalline powder

Solubility

Freely soluble in water and in glacial acetic acid, practically insoluble in acetone and in alcohol.

Identification

Infrared absorption spectronphotometry, IR    spectrum is in concordance with Tranexamic acid CRS

PH

7.0-8.0

Related substances Liquid chromatography

Impurity A:≤0.1%

Impurity B: ≤0.2%

Any other impurity: ≤0.1%

All other impurity: ≤0.2%

Heavy metals

≤10ppm

Chlorides

≤140ppm

Loss on drying

≤0.5%

Residue on ignition

≤0.1%

Sulphated ash

≤0.1%

Assay

99.0%-101.0%

Function

Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver, vascular and large orthopedic procedures. 

Tranexamic acid has been found to decrease the risk of death in people who have significant bleeding due to trauma. However, it may actually increase the risk of death due to bleeding if administered more than 3 hours after the injury. 

Heart surgery

Tranexamic acid is commonly used in cardiac surgery, both with and without cardiopulmonary bypass. It replaces aprotinin. 

Menstrual bleeding

Used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. A recent study showed patients treated with tranexamic acid are more likely to develop thrombosis and necrosis in their fibroids, and may result in pain and fever. 

Whitening effect

Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%.

Standard: BP2015
Solubility: Soluble in water 
Storage: Protected from light and humidity in a clean place at room temperature. Once open, handle with care to avoid secondary microbial contamination. 
Country of Origin: China 
Shelf Life: 4 years

This product should be added to a formulation at the recommended usage rate for cosmetic ingredients.

Shipping Information: HS Code: 29224911.00

Packing:25kg /drum


 


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